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exerciseneurogenesisFeatured

Exercise-Induced Neurogenesis: The BDNF Mechanism Explained

How aerobic exercise drives hippocampal neurogenesis via BDNF: lactate and irisin mechanisms, Erickson 2011 human evidence, and zone 2 vs HIIT dose-response.

12 min read
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adenosinesleep pressure

Adenosine and Sleep Pressure: The Neuroscience of Process S

How adenosine builds during wakefulness to drive sleep pressure: A1/A2A receptors, basal forebrain circuitry, caffeine antagonism, and glymphatic clearance.

12 min read
psilocybinneuroplasticity

Psilocybin Neuroplasticity: 2026 Research Overview

An evidence review of psilocybin's mechanisms in neuroplasticity research: BDNF/TrkB signalling, dendritic spine growth, and Australia's prescriber pathway.

11 min read
Alzheimer'sdementia prevention

Alzheimer's Prevention Research: What the Evidence Shows

The 2024 Lancet Commission found 45% of dementia is preventable. A research overview of modifiable risk factors, FINGER trial, anti-amyloid drugs, and BDNF.

12 min read
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IGF-1neurotrophic factor

IGF-1 and the Brain: Neurotrophic Research

A research overview of insulin-like growth factor 1 in the brain: how it reaches and is made in the CNS, its receptor signalling, its neurotrophic roles in neurogenesis and plasticity, and the mixed evidence on IGF-1 and cognition.

5 min read
GABAnootropics

GABA Pathway Nootropics: Anxiety and Sleep Evidence

An evidence-grounded review of the GABAergic system and the compounds that modulate it, from phenibut to ashwagandha, with honest risk-benefit analysis.

11 min read
dopamineneuroscience

Dopamine Optimization: The Neuroscience of Motivation, Focus and Reward

A rigorous neuroscience guide to the dopamine system: synthesis, receptors, tonic vs phasic firing, reward prediction error, and evidence-based ways to support it.

13 min read
Pinealonbioregulator

Pinealon: The Khavinson Bioregulator Peptide Guide

Pinealon is a Glu-Asp-Arg tripeptide from the Khavinson bioregulator school, proposed to modulate gene expression. This review covers the claims and data.

11 min read
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4Neuroscience is an independent research hub synthesising peer-reviewed studies on nootropic peptides, cognitive neuroscience, and human performance, written for researchers, students, and health-conscious Australians.

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